Abstract

Granulomatous polyangiitis (GPA), previously known as Wegener's granulomatosis, is the most common form of life-threatening vasculitis. Although its exact pathogenesis is not known, GPA is considered to be its own due to the presence of anti-neutrophil cytoplasmic antibodies with cytoplasmic staining pattern (c-ANCA) expressed in activated neutrophils. Widespread complex of immune diseases. GPA mainly affects the upper and lower respiratory tracts and kidneys, but it can also cause damage to multiple organ systems. The classic clinical triad of the so-called GPA includes sinusitis, pneumonia and glomerulonephritis. GPA patients have a high risk of death and can cause sudden death. Therefore, early diagnosis and timely treatment are very important. This article aims to improve the understanding of Wegener's granulomatosis in the case of a patient with Wegener granulomatosis and to improve patient prognosis through close interdisciplinary collaboration[1,2].

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