Abstract
A 10-year-old boy had a long time of fever, and was diagnosed as JRA at first, but the patient’s condition got worse and worse after the treatment, then we did the cervical lymph node biopsy, which showed ALCL (Anaplastic Large Cell Lymphoma). After receiving the correct treatment, the patient’s condition got better.
Highlights
Fever of unknown origin (FUO) refers to a condition in which the patient has an elevated temperature, but no explanation has been found in spite of investigations by a physician
A general diagnosis of non-Hodgkin lymphomas (NHL) is accurate in roughly 90% of cases; consensus among pathologists regarding the identification of specific histologic subtypes occurs only slightly more than half of the time in past studies using morphology only
ALCL is the most common mature T-cell lymphoma seen in children and makes up approximately 10% of all paediatric NHL and approximately 30% - 40% of the large-cell lymphomas seen in the paediatric population [3]
Summary
Fever of unknown origin (FUO) refers to a condition in which the patient has an elevated temperature, but no explanation has been found in spite of investigations by a physician. The cause is found by eliminating all possibilities until only one explanation remains, and taking this as the correct one, it is usually a diagnosis of exclusion
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