A case report of breast cancer in breast augmentation surgery with injection of free liquid silicone

Abstract

Breast augmentation surgery with an injection of free liquid silicone has been performed from the early 1960s but was abandoned by most practitioners because numerous complications have been reported, such as migration of silicone to other parts of the body, inflammation, discoloration, and the formation of granulomas, ulceration and fistulae, anaplastic large cell lymphoma, Silicone-Induced Granuloma, breast carcinoma. In this case report, we describe an invasive breast carcinoma, diagnosed via core needle biopsy, in breast augmentation by injecting free liquid silicone ten years ago, including breast imaging findings on mammography and MRI, macroscopic and microscopic features. The nipple-sparing mastectomy was performed for two breasts that were injected with liquid silicone. In the right breast with adenocarcinoma, surgical margins above nipple-areolar were assessed intra-operatively by frozen section before immediate breast reconstruction was carried out in the same operation. TRAM flap procedure reconstructed for right breast and implant breast reconstruction for the left breast. We received amazing post-operative results. Key words: breast cancer, liquid silicone injection, breast reconstruction