Abstract
A lung transplant (LT) patient developed two distinct episodes of COVID-19, confirmed by whole-genome sequencing, to be caused by the Delta, followed 6-weeks later by the Omicron variant. The clinical course with Omicron was more severe, leading us to speculate that Omicron may not be any milder among LT patients.We discuss the potential mechanisms behind the Omicron not being any milder among LT patients and emphasize the need for the outcomes data among these patients. Till such data becomes available, it may be prudent to maintain clinical equipoise as regards the relative virulence of the newer variants among LT patients.
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