Abstract
BackgroundThe clinical incidence of appendiceal mucinous adenocarcinoma is low. Moreover, the case reports of postoperative relapse after surgery are rarely based on literature search results. Here, we report such a case spanning nearly 7 years and and review the relevant literature.Case presentationA 50-year-old female underwent additional surgery after appendectomy, and pathological examination confirmed mucinous adenocarcinoma. The patients underwent HIPEC (hyperthermic intraoperative chemotherapy) and adjuvant chemotherapy. Twenty-six months after the previous surgeries, another surgery, HIPEC, and adjuvant chemotherapy were performed again due to tumour recurrence. To date, the follow-up time is 43 months, and no recurrence or metastasis has been found.ConclusionsAppendix mucinous adenocarcinoma has a poor prognosis and the diagnosis depends on pathological and immunohistochemical examinations. Its clinical manifestations are non-specific, and CRS + HIPEC should be used for treatment, which is safe and effective.
Highlights
The clinical incidence of appendiceal mucinous adenocarcinoma is low
Its clinical manifestations are non-specific, and Complete cytoreductive surgery (CRS) + Hyperthermic introperitoneal Chemotherapy (HIPEC) should be used for treatment, which is safe and effective
Appendiceal adenocarcinoma accounts for < 0.5% of all gastrointestinal neoplasms. it is extremely difficult to diagnose prior to surgical inspection, and it usually depends on the pathology following appendectomy [1]
Summary
Appendix mucinous adenocarcinoma has a poor prognosis and the diagnosis depends on pathological and immunohistochemical examinations.
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