Abstract
Reticular erythematous mucinosis is an uncommon type of cutaneous mucinosis. Typically, reticular erythematous mucinosis affects middle-aged women and usually appears as papules and plaques on the mid-upper trunk. Histologically, biopsies of reticular erythematous mucinosis reveal increased deposition of dermal mucin and perivascular lymphocytic inflammation. Infrequently, reticular erythematous mucinosis has been reported in males and in atypical locations other than the trunk. In these instances, reticular erythematous mucinosis can present a diagnostic challenge clinically and histologically. This case describes the clinical and histologic findings of a localized variant of reticular erythematous mucinosis in a 65-year-old male patient.
Highlights
Reticular erythematous mucinosis (REM) is classified as a primary mucinosis of the skin in which there is an increased deposition or accumulation of mucin within the dermis.[1]
Despite initial observation in the 1960s,3,4 there is continued debate regarding the etiology of REM and whether it truly is separable from other dermatologic conditions including cutaneous manifestations of lupus erythematosus.[5]
Additional research has improved the clinical and histological understanding of REM and has helped inform practice recommendations.[6]. This case report presents the distinct case of a 65-year-old male with a localized variant of REM on the lower legs
Summary
Reticular erythematous mucinosis (REM) is classified as a primary mucinosis of the skin in which there is an increased deposition or accumulation of mucin within the dermis.[1]. Middle-aged women are predominantly affected (2:1 female:male prevalence ratio).[2] Despite initial observation in the 1960s,3,4 there is continued debate regarding the etiology of REM and whether it truly is separable from other dermatologic conditions including cutaneous manifestations of lupus erythematosus.[5] Additional research has improved the clinical and histological understanding of REM and has helped inform practice recommendations.[6] This case report presents the distinct case of a 65-year-old male with a localized variant of REM on the lower legs.
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