Abstract
Background: Thin-cap fibroatheroma (TCFA) and necrotic core characterises highest-risk plaques, which acutely rupture. Likelihood of TCFA increases with severity of stenosis but is more common in mildly stenotic lesions. Optical coherence tomography and intravascular ultrasound have been used to quantify fibrous cap thickness and plaque vulnerability at angiography. Computed tomographic coronary angiography (CTCA) may be useful in diagnosing and monitoring vulnerable plaque, although the thin cap cannot be specifically demonstrated.
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