Abstract
A 48 year old male with perianal abscess was given intramuscular injections of RSM 2gm. per day for 6 days, then a combination of RSM 1gm. and DKB 100mg per day for one day, followed by DKB 200mg per day for 8 days. He complained of equilibrium disturbances when the dose of RSM reached 13gm, and DKB (dose level unclear). The chief complaint on his first visit was not deafness but disturbance of standing and walking and of visual fixation while walking and running (jumbling phenomenon). The equilibrium test showed a marked disturbance of standing with eyes closed. Labyrinthine excitability was greatly decreased bilaterally.The galvanic nystagmus test revealed that the site of damage was the vestibular neuroepithelium.The rotatory responses had recovered slightly about 5 months after the onset.
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