Abstract
Summary We report a case of an 84-year-old widow from Taiwan who meets a classic presentation of symptomatology from very late-onset schizophrenia-like psychosis (VLOSLP). After 2 decades of reference idea, she subsequently suffered from persecutory, partition delusion and multimodal hallucinations. Acute psychiatric hospitalization was arranged for diagnostic workup and antipsychotics treatment. No laboratory abnormalities were found. We gave olanzapine and gradually titrated to 20 mg/day, and her psychotic symptoms were relieved in a month, then discharged. This case report is aimed to discuss the clinical characteristics, nosology, and treatment of VLOSLP. Further exploration of VLOSLP should be considered because of its unique clinical feature and course.
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