Abstract
Imigran ® (sumatriptan, a 5-hydroxytryptamine (HT derivative, is highly effective in aborting attacks of migraine and cluster headache. The drug is generally well tolerated. However tolerated, although up to 8% of patients consistently have demonstrate chest symptoms, including chest pressure, tightness, and pain, often mimicking angina pectoris. It has been suggested that these chest symptoms are caused by coronary vas- oconstriction, and that this effect may be mediated by endothelial dysfunction. This can be reversed by the administration of glyceryl trinitrate. We report a case of vasospastic angina pectoris occurring after the adm- inistration of oral sumatriptan in a patient with migraine. (Korean Circulation J 2001;31( ( ( (10 :1071-1074
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