Abstract

BackgroundOcular and extraocular immune-mediated phenomena are known to occur following febrile illness. Vasculitis, retinitis and neurosensory detachment are not well-recognized sequelae of typhoid fever.FindingsWe report a case of vasculitis, retinitis and macular neurosensory detachment presenting post typhoid fever. A 27-year-old female presented with decreased vision in right eye with history of typhoid fever (treated adequately 6 weeks prior). Her best corrected visual acuity in right eye was 20/125, N36. Fundus showed a patch of vasculitis and retinitis superior to the disc associated with macular neurosensory detachment and disc pallor. With oral steroids, the inflammation resolved and visual acuity improved to 20/20 at 6 weeks.ConclusionsImmune-mediated vasculitis and retinitis following typhoid fever may respond well to systemic steroids.

Highlights

  • Ocular and extraocular immune-mediated phenomena are known to occur following febrile illness

  • Our group published [2,3] late-onset endogenous endophthalmitis post typhoid fever resolution. In this manuscript we report a patient who presented with retinitis and had a history of typhoid fever, beginning 6 weeks prior to presentation

  • Case report A 26-year-old Indian female presented in urban southern India, at LV Prasad Eye Institute, Hyderabad, with sudden, painless decreased vision in the right eye for 20 days associated with floaters

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Summary

Introduction

Ocular and extraocular immune-mediated phenomena are known to occur following febrile illness. Our group published [2,3] late-onset endogenous endophthalmitis post typhoid fever resolution. In this manuscript we report a patient who presented with retinitis and had a history of typhoid fever, beginning 6 weeks prior to presentation.

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