Abstract
Objective Systemic sclerosis sine scleroderma (ssSSc) is a rare type of systemic sclerosis, comparison between ssSSc and other types of systemic sclerosis (SSc), ssSSc is carried out in this study. Methods We reported a patient with Raynaud's phenomenon, esophagus, intestine and lung involvement, positive ANA, anti-Scl-70 antibody, but had no skin sclerosis. Results For visceral involvement, ssSSc was not different from limited cutaneous systemic sclerosis (lcSSc), The incidence of pulmonary hypertension was higher in patients with ssSSc, lower with calcinosis, finger ulcer and acral dissolution, and the incidence of ssSSc and lcSSc interstitial lung disease was higher than that of diffuse cutaneous systemic sclerosis, (dcSSc). Conclusion Although ssSSc do not have skin sclerosis, however, visceral involvement is more extensive. Early diagnosis and treatment is extremely important. Key words: Scleroderma, systemic; Systemic sclerosis sine scleroderma; Scleroderma, localized
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