Abstract

Case summary: A 37-year-old woman presented with a mass around the punctum in the right lower eyelid margin, which had developed several years earlier and was increasing in size. The mass was a light pinkish nodule consisting of a few smooth-surface papillary lobules. The pathologic findings of the specimen obtained from a shaving biopsy showed a papil- lary projection which was covered with epithelium and communication with duct-like structures showing glandular config- uration in the deep portion of the lesion. EMA-positive cells were found at the invaginated epithelium, implying a glandular epithelial origin. GCDFP-15-positive cells were found in the deep portion of the lesion, implying apocrine differentiation. The findings were compatible with syringocystadenoma papilliferum. Conclusions: Syringocystadenoma papilliferum should be considered as a differential diagnosis of a solitary eyelid tumor. J Korean Ophthalmol Soc 2012;53(7):1023-1026

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