Abstract
We recently experienced a case of very uncommon subareolar duct papillomatosis of the right nipple. The patient was a 30-year-old, unmarried woman with a firm, painless mass measuring 1.3×1.3cm in her right nipple. A biopsy specimen was pathologically misinterpreted as invasive carcinoma and radical mastectomy was carried out. Various diagnostic terms have been used for this entity in the literature. These include adenoma of the nipple, papilloma of the nipple, florid papillomatosis of the nipple ducts, erosive adenomatosis of the nipple and so on. The number of cases previously reported under these various terms in Japan is 12 (including ours). In each case, a mass was clinically found in the nipple or subareolar region. Histologically, there was marked proliferation of ducts in the stroma of the nipple producing a pattern that could be mistaken for invasive carcinoma. It is therefore important to bear this rare lesion in mind and perform a thorough examination before making a diagnosis of a mass in the breast.
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