Abstract
A case of stomal carcinoma occurred 48 years after gastrojejunostomy for benign pyloric stenosis is reported. The case involved a 72year-old man who underwent a gastrojejunostomy in the upper body on the greater curvature for benign pyloric stenosis in 1945. In 1985, a stomal ulcer was detected by endoscopic examination, and thereafter he received the endoscopic examination every year. In 1993, histological study of biopsy specimens from the stomal ulcer showed moderately differentiated adenocarcinoma, and total gastrectomy and resection of the stoma including the jejunum were performed on March 22, 1994. Resected specimen revealed another ulcer lesion besides the ulcer lesion shown with endoscopic study. Histological examination of this lesion confirmed signet ring cell carcinoma. Moreover, microscopic finding revealed the features of gastritis cystica polyposa under the cancer lesion in the submucosal region. A total of 33 cases of gastric cancer following gastrojejunostomy without gastrectomy have been reported in Japan, indicating a correlation between regurgitation of bile juice and carcinogenesis.
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