Abstract

A rare case of solid and cystic tumor of the pancreas is described with a review of 121 collective cases reported in Japan.A 22-year-old woman consulted our hospital because of continuous upper abdominal pain. A fist-sized tumor was palpated in the right upper abdomen. CT scan showed a cystic tumor located in the head of the pancreas, with the size of 15 cm in diameter. The patient was operated on. The tumor was well encapsulated with a firm, white, fibrous capsule, and was resected. No infiltration into the pancreas parenchyma was noted.On the cut surface, the tumor was composed of solid and cystic lesions, with necrotic and hemorrhagic materials. Microscopically the tumor tissue showed pseudopapillary stractures with numerous PAS-positive granules. Some of tumor cells were positive for α1-antitrypsin. Electron micrograph showed that tumor cells were rich in mitochondria, and some of them contained zymogen-like granules. From these findings the diagnosis of solid and cystic tumor was made. The patient is doing well up to now, 12 months after surgery. A total of 122 cases including this case seen in the Japanese literature were reviewed to clarify the clinical and clinicopathological features.

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