A Case of Secondary Oral Syphilis Presenting with Milk Patches in the Buccal Mucosa

Abstract

We report a case of secondary oral syphilis presenting with milk patches in the buccal mucosa. A 43-year-old man presented in our hospital because of gingival pain from brushing his teeth. In the bilateral buccal mucosa he had milk patches surrounded by painless erythema with a clear borderline. Multiple submandibular lymph node swellings were palpable, but general eruptions were absent. On serological examination, the RPR test result was x64 and the TPHA result was > 40,960, so a diagnosis of secondary oral syphilis was made. Oral lesions disappeared after the administration of AMPC 750 mg/day for three weeks.