Abstract
BackgroundSolid pseudopapillary neoplasm of the pancreas is a rare tumor in young women, metastasizing in only 5–15% of cases, and most commonly to the liver. Although treatment guidelines have not been established, surgical resection is usually performed. We report a rare case of repeat hepatectomy for liver metastases after distal pancreatectomy with solid pseudopapillary neoplasm.Case presentationThe patient was a 71-year-old woman who underwent distal pancreatectomy for solid pseudopapillary neoplasm, and liver metastasis occurred 4 years after the first surgery. Partial liver resection was performed for four liver metastases, and histopathological examination revealed a diagnosis of liver metastasis from solid pseudopapillary neoplasm. However, 18 months later, liver metastases were detected again; three tumors were identified, and partial resection was performed, which has provided 18 months’ recurrence-free survival.ConclusionsLong-term prognosis can be expected following R0 resection for resectable liver metastasis from solid pseudopapillary neoplasm.
Highlights
Solid pseudopapillary neoplasm of the pancreas is a rare tumor in young women, metastasizing in only 5–15% of cases, and most commonly to the liver
We report a case of repeat hepatectomy for liver metastasis from Solid pseudopapillary neoplasm (SPN)
Immunohistostaining studies revealed that the tumor cells were positive for vimentin, synaptophysin, cluster of differentiation (CD) 56, β-catenin, CD10, and progesterone receptor
Summary
Solid pseudopapillary neoplasm of the pancreas is a rare tumor in young women, metastasizing in only 5–15% of cases, and most commonly to the liver. SPN metastasizes in only 5–15% of all cases, and common sites include the liver, spleen, omentum, peritoneum, duodenum [4], 5. *Correspondence: hdobaba@kumamoto‐u.ac.jp 2 Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, 1‐1‐1 Honjo, Chuo‐ku, Kumamoto 860‐8556, Japan Full list of author information is available at the end of the article is unclear. We report a case of repeat hepatectomy for liver metastasis from SPN.
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