Abstract
A case of recurrent ventriculitis associated with Colistin-Resistant Klebsiella pneumoniae in patient with ventriculoperitoneal shunt treated with intrathecal amikacin
Highlights
Carbapenem-resistant Klebsiella pneumoniae (CR-KP) strains have been increasingly seen as agents in the nosocomial infections in recent years
Extraventricular drainage (EVD) was replaced a total of 10 times during six months, due to carbapenem resistant Acinetobacter baumannii and CR-KP [ertapenem MIC>16 Colistin MIC=0.75 mcg/mL] agents which isolated from cerebrospinal fluid (CSF) culture and even with intravenous and intrathecal colistin therapy which were combined with other antibiotics, we could not achieve clinical improvement in the patient during 75 days of treatment
Kaya A (2019) A case of recurrent ventriculitis associated with Colistin-Resistant Klebsiella pneumoniae in patient with ventriculoperitoneal shunt treated with intrathecal amikacin therapy and consciousness of the patient was opened on the 15th days of the amikacin and Glasgow coma score (GCS) was increased from 9/15 to 14/15 and subsequently the patient was discharged from intensive care unit for regular physiotherapy and supportive treatment on the 25th days of the cure, she returned to normal life with the recent therapies
Summary
Carbapenem-resistant Klebsiella pneumoniae (CR-KP) strains have been increasingly seen as agents in the nosocomial infections in recent years. The condition of the patient worsened under this treatment and colistin-resistant Klebsiella pneumoniae (CoR-KP) was isolated from cerebrospinal fluid (CSF) culture. She could be successfully treated with intravenous and intrathecal amikacin use. EVD was replaced a total of 10 times during six months, due to carbapenem resistant Acinetobacter baumannii and CR-KP [ertapenem MIC>16 Colistin MIC=0.75 mcg/mL] agents which isolated from CSF culture and even with intravenous and intrathecal colistin therapy which were combined with other antibiotics, we could not achieve clinical improvement in the patient during 75 days of treatment. Kaya A (2019) A case of recurrent ventriculitis associated with Colistin-Resistant Klebsiella pneumoniae in patient with ventriculoperitoneal shunt treated with intrathecal amikacin. Therapy and consciousness of the patient was opened on the 15th days of the amikacin and Glasgow coma score (GCS) was increased ( improved) from 9/15 to 14/15 and subsequently the patient was discharged from intensive care unit for regular physiotherapy and supportive treatment on the 25th days of the cure , she returned to normal life with the recent therapies
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