Abstract
The Journal is the primary organ of Continuing Paediatric Medical Education in Sri Lanka. The journal also has a website. Free full text access is available for all readers.The Sri Lanka Journal of Child Health is now indexed in SciVerse Scopus (Source Record ID 19900193609), Index Medicus for South-East Asia Region (IMSEAR), CABI (Centre for Agriculture and Bioscience International Global Health Database), DOAJ and is available in Google, as well as Google Scholar.The policies of the journal are modelled on the Committee on Publication Ethics (COPE) Guidelines on Principles of Transparency and Best Practice in Scholarly Publishing. Sri Lanka Journal of Child Health is recognised by the International Committee of Medical Journal Editors (ICMJE) as a publication following the ICMJE Recommendations.
Highlights
Tumefactive demyelinating lesion (TDL) is defined as a solitary demyelinating lesion larger than 2 cm[1]
Tumefaction is an uncommon cause of demyelination and can be missed in the absence of clinical suspicion
Role of B cell-mediated immunity is proposed exact pathogenesis is not clear[6]
Summary
Tumefactive demyelinating lesion (TDL) is defined as a solitary demyelinating lesion larger than 2 cm[1]. Many patients have a history of multiple sclerosis (MS)[2]. It might present with intracranial space occupying lesion (SOL) like effects[3]. Tumefactive lesions should be differentiated from other causes of SOL in the brain for appropriate management. Both tumefactive demyelination (TD) and tumefactive multiple sclerosis (TMS) are very uncommon in children. We report a case of TD or TMS in an adolescent girl who developed recurrent central nervous system (CNS) symptoms over a span of 1.5 years. Child started improving and started to go to school after two months of starting treatment. For around 14 months, the child was well except for minimal residual weakness in the left arm
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