Abstract

ABSTRACTCaseReactive hypoglycemia can occur due to postprandial insulin hypersecretion. However, no Kampo medicine is known to cause this effect. Herein, we describe a case of reactive hypoglycemia that occurred postprandially as an effect of Kampo medicine. A 42‐year‐old woman was admitted because of chest pain. We prescribed saikokaryukotsuboreito, following which the patient's symptoms improved. However, after 9 months, she experienced persistent fatigue after developing a cold. Therefore, we changed the prescription to hochuekkito and keishikaryukotsuboreito. Nevertheless, discomfort in the epigastric region and back pain developed within a few hours after administration of these medications.OutcomeResults of 75 g oral glucose tolerance test (OGTT) showed excessive insulin secretion, potentially as a result of changing Kampo administration. Therefore, the treatment was changed back to saikokaryukotsuboreito, which resolved the postprandial symptoms. Moreover, the insulin hypersecretion disappeared on subsequent 75 g OGTT.ConclusionThe promotion of gastric peristaltic function as an effect of Kampo may cause reactive hypoglycemia.

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