A case of pseudomyxoma peritonei with pleural recurrence in which long-term survival was achieved by pleurectomy and intrathoracic chemotherapy

Abstract

A 61-year-old female who underwent cytoreductive surgery for pseudomyxoma peritonei showed left pleural recurrence 2 years later. Disseminated tumors were widely observed in the whole parietal pleura, the lung surface and the diaphragm. Left parietal pleurectomy and decortications of the lung were performed. Intrathoracic chemotherapy with CDDP was added after resection. The postoperative course was uneventful, and the patient was discharged on the 33rd postoperative day. She has undergone repeat cytoreductive surgeries twice for abdominal recurrence to date. At 62 months after thoracic cytoreduction, she maintained a disease-free status with a good quality of life. This is the first report showing that long-term survival longer than 5 years was achieved with a disease-free state by pleurectomy and intrathoracic chemotherapy.