Abstract

Systemic lupus erythematosus (SLE) is a multigenic disease leading to chronic inflammatory states within organ systems. When associated with ascites, pleural effusions, and elevated CA-125 levels, it is known as pseudo-pseudo Meigs syndrome. It is a clinical diagnosis without findings of benign or malignant ovarian tumors in patients with SLE. We present a patient case of a 42-year-old woman who presented with episodic and progressively worsening ascites, bilateral pleural effusions, and elevated CA-125 levels without any evidence of benign or malignant tumors as the initial manifestation of SLE.

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