Abstract

7 Tag CG, Schifflers MC, Mohnen M, Gressner AM, Weiskirchen R.Atypical melting curve resulting from genetic variation in the 3 un-translated region at position 20218 in the prothrombin gene analyzedwith the LightCycler factor II (prothrombin) G20210A assay. ClinChem 2005; 51: 1560–1.8 Wylenzek M, Geisen C, Stapenhorst L, Wielckens K, Klingler KR. Anovel point mutation in the 3 region of the prothrombin gene atposition 20221 in a Lebanese/Syrian family. Thromb Haemost 2001;85: 943–4.9 Balim Z, Kosova B, Falzon K, Bezz ina Wettinger S, Colak Y. Budd-Chiari syndrome in a patient heterozygous for the point mutationC20221T of the prothrombin gene. J Thromb Haemost 2003; 1: 852–3.10 Lyon E.Discovering rare variantsb yuseofmeltingtemperatureshiftsseen in melting curve analysis. Clin Chem 2005; 51: 1331–2.11 Hooper WC, Roberts S, Dowling N, Austin H, Lally C, Whitsett C.The prevalence of the prothrombin gene variant C20209T in African-Americans and Caucasians and lack of association with venousthromboembolism. Thromb Res 2006; 118: 767–8.12 Itakura H, Telen MJ, Hoppe CC, White DA, Zehnder JL. Char-acterization of a novel prothrombin variant, Prothrombin C20209T,as a modifier of thrombotic risk among African-Americans. J ThrombHaemost 2005; 3: 2357–9.13 DanckwardtS,HartmannK,KatzB,HentzeMW,LevyY,EicheleR,Deutsch V, Kulozik AE, Ben-Tal O. The prothrombin 20209 C–>Tmutation in Jewish-Moroccan Caucasians: molecular analysis of gain-of-function of 3 end processing. J Thromb Haemost 2006; 4: 1078–85.14 DanckwardtS,HartmannK,GehringNH,HentzeMW,KulozikAE.3 end processing of the prothrombin mRNA in thrombophilia. ActaHaematol 2006; 115: 192–7.15 Ceelie H, Spaargaren-Van Riel CC, Lyon E, Bertina RM, Vos HL.Functional analysis of two polymorphisms in the 3 -UTR of the hu-man prothrombin gene. J Thromb Haemost 2005; 3: 806–8.16 van der Putten HH, Spaargaren-van Riel CC, Bertina RM, Vos HL.Functional analysis of two prothrombin 3 -untranslated region var-iants: the C20209T variant, mainly f ound among African-Americans,and the C20209A variant. JThrombHaemost2006; 4: 2285–7; authorreply 2288–9.17 Danckwardt S, Hartmann K, Katz B, Ben-Tal O, Kulozik AE. Moreon: functional analysis of two prothrombin 3 UTR variants: theC20209T variant, mainly found among African-Americans, and theC20209A variant. J Thromb Haemost 2006; 4: 2288–9.18 Ceelie H, Bertina RM, van Hylckama Vlieg A, Rosendaal FR, VosHL. Polymorphisms in the prothro mbin gene and their associationwith plasma prothrombin levels. Thromb Haemost 2001; 85: 1066–70.19 Perez-Ceballos E, Corral J, Alberca I, Vaya A, Llamas P, Montes R,Gonzalez-Conejero R, Vicente V. Prothrombin A19911G andG20210A polymorphisms role in thrombosis. Br J Haematol 2002;118: 610–4.20 Danckwardt S, Gehring NH, Neu-Yilik G, Hundsdoerfer P, PforsichM, Frede U, Hentze MW, Kulozik AE. The prothrombin 3 end for-mation signal reveals a unique architecture that is sensitive to throm-bophilic gain-of-function mutations. Blood 2004; 104: 428–35.21 Gurgey A, Unal S, Okur H, Duru F, Gumruk F. ProthrombinG20210A mutation in Turkish children with thrombosis and the fre-quency of prothrombin C20209T. Pediatr Hematol Oncol 2005; 22:309–14.

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