A CASE OF PRIMARY SPLENIC ANGIOSARCOMA OF WHICH CLINICAL COURSE WAS ABLE TO BE OBSERVED

Abstract

We present a rare case of primary splenic angiosarcoma of which clinical course was able to be observed, together with a review of the literature. A 56-year-old woman visited another hospital because of left upper abdominal pain and body weight loss which started in december 1994. She was recommended for admission because of abnormality of the spleen but regected, when no hepatic tumor was reveraled on CT. Later, she was admitted to the hospital because the abdominal symptom persisted in February 1996. On physical examination at admission, to spleen was palpable four finger's width in the left quadrant of the abdomen. Laboratory studies revealed severe anemia, hemorrhagic tendency, thrombocytopenia and liver dysfunction. A primary splenic angiosarcoma with multiple metastasis to the liver and bone was considered from radiologic findings. After the pathohistological diagnosis was confirmed by biopsy, IL-2 which is considered to have therapeutic effect only to angiosarcoma in this time was administered systemically. But the symptoms progressed worse, and the patient died 57days after the admission. This time, we experienced a case of primary splenic angiosarcoma that is vey rare, and reported it with some discussion of literatures.