Abstract

A case of primary pulmonary cryptococcosis is reported. A 76-year-old man, without underlying disease or immunological abnormalities, was admitted to the hospital. Chest X-ray revealed diffuse infiltrative shadows considered at first to be community-acquired pneumonia. A diagnosis of pulmonary cryptococcosis was performed using fluconazole, miconazole and transbronchial inhalation of amphotericin B. Cryptococcal antigen detection was performed by two latex agglutination methods: Crypto-test and Sero-direct test (Eiken-test). Comparing the results of the two tests, sensitivity was superior with the Sero-direct test, but the correlation between the titers of the two tests was good.

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