A Case of Postoperative Multiple Organ Metastases from Renal Ewing Sarcoma and Review of the Literature

Abstract

The incidence of extra-osseous Ewing sarcoma is low, and extra-osseous Ewing sarcoma of renal origin is even less frequently reported. The clinical manifestation of Ewing sarcoma is non-specific and early diagnosis is difficult, and the diagnosis mainly relies on pathological histology and immunohistochemistry. The disease is highly malignant, with a high rate of local recurrence and distant metastasis, and is currently treated with a combination of surgery, chemotherapy and radiation therapy. The Department of Urology of the First Affiliated Hospital of Jinan University admitted a 71-year-old male patient in 2021 with carnal hematuria and lumbar and abdominal pain as the first manifestation, and the preoperative examination showed a type of round mixed signal mass in the right kidney. After admission, the patient underwent mass resection and inferior vena cava dissection, and the postoperative pathology showed a small round cell malignant tumor, which was considered as extraosseous Ewing sarcoma in combination with immunohistochemical results. Three weeks after surgery, the patient developed multiple organ metastases.