A Case of Plexiform Neurofibroma Arising from Laryngeal Surface of Epiglottis

Abstract

Neurofibroma is characterized as a benign, slow growing neoplasm, originating from Schwann cells or fibroblast in peripheral nerve sheaths. It may appear as a solitary tumor or have multiple localizations in von Recklinghausen disease. They are commonly found in the gastrointestinal tract and laryngeal neurofibromas are extremely rare, accounting for only 0.03 to 0.1% of benign tumors of the larynx. The aryepiglottic fold and arytenoid are the common site of occurrence for laryngeal neurofibroma, because the branch of the superior laryngeal nerve is involved. We present a case of solitary plexiform neurofibroma arising from the laryngeal surface of epiglottis in a 55-year old female who found the lesion incidentally. We removed the tumor completely by transoral laser surgery and no recurrence was found after 7 months. The case of solitary neurofibroma arising from laryngeal surface of epiglottis has not been reported in Korea. We report this case regarding the diagnosis and treatment with review of literatures. Key words: Plexiform neurofibroma ㆍ Larynx ㆍ Epiglottis ㆍ CO2 laser 핵심용어: 망상형 ì‹ ê²½ì„¬ìœ ì¢ ã† 후두 ㆍ 후두개 ㆍ ë ˆì´ì €ìˆ˜ìˆ