Abstract

THIS CASE is reported to demonstrate the therapeutic effect of antuitriri′G on growth in a pituitary dwarf, on whom the causal factor of dwarfism was active. Pituitary dwarfism may be due to an idiopathic insufficiency of the eosinophilic cells ofthe anterior lobe of the hypophysis, or result from pressure upon these cells, with subsequent atrophy. The pressure may be produced by an overgrowth of other types of cells in the pituitary gland, as a chromophobic or basophilic adenoma. The pressure upon the gland may also result from increase in size of surrounding structures, as tumors or inflam′ matory lesions in the hypothalamic area. Cases illustrating these various causal factors are described by Cushing (i), Bailey (2), Weber (3), Dott and Bailey (4), Mott and Barrett (5), Beckmann and Kubie (6), Critchley and Ironsides (7), and Zeitlin (8), as well as others. Chromophobe adenomata in childhood and adolescence are rare.

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