Abstract
ABSTRACT Paucisymptomatic unilateral isolated optic disc edema (UIODE) is an uncommon exam finding that presents a challenge to the clinician due to its broad, heterogenous differential diagnosis. We describe the case of a 77-year-old man with known Waldenstrom macroglobulinemia (WM) who presented with paucisymptomatic UIODE found to be the presenting sign of Bing–Neel Syndrome. This case emphasizes the wide array of diagnoses that can lead to the presentation of paucisymptomatic UIODE, as well as the challenges of diagnosing Bing–Neel Syndrome in patients with nonspecific symptoms and exam findings. To our knowledge, this is the first case of paucisymptomatic UIODE as the presenting sign of Bing–Neel Syndrome in English literature.
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