Abstract
Pancreatic Neuroendocrine Carcinoma (PanNEC) is a rare type of cancer with rapid progression and a poor prognosis. In this report, we present a case of PanNEC that was diagnosed after a dramatic change in its imaging features. A 73-year-old woman with upper abdominal pain was referred to our hospital for evaluation of a 28 mm cystic mass found on abdominal computed tomography. The tumor was also visualized as a cyst on endoscopic ultrasound and did not enhance, but it compressed the main pancreatic duct. Two months later, the tumor had increased in size (50 mm) and transformed into a solid lesion. Pathological findings from a specimen obtained by EUS-FNA revealed that the tumor was PanNEC with a Ki-67 index of >80%. The patient’s survival time was only 4 months after the onset. In considering a case of an uncommon pancreatic mass, it’s important to bear in mind the possibility that it could be PanNEC.
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