Abstract
A 20-month-old female beagle showed a pancreatic nesidioblastosis with a curious proliferation of islet hormone-positive cells. These cells were characterized by a tubular or columnar pattern, occasionally with a rosette-like structure. Immunohistochemistry revealed that they were positive to insulin and chromogranin A and weakly-positive to glucagon and somatostatin in the cytoplasm, but negative for cytokeratin. PCNA- positive cells were also scattered among these proliferating cells. The present case appears to be a specific type of nesidioblastosis accompanied by a proliferation of previously unidentified islet-cells in a beagle.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
