A Case of Orf Disease Complicated with Erythema Multiforme and Bullous Pemphigoid-Like Eruptions.

Shahriar Alian,Sara Arabsheybani,Fatemeh Ahangarkani

doi:10.1155/2015/105484

Shahriar Alian, Sara Arabsheybani + Show 1 more

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https://doi.org/10.1155/2015/105484

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Abstract

Parapoxvirus infection in sheep and goats is usually referred to as contagious pustular dermatitis/ecthyma, or orf, and the corresponding human infection is referred to as orf. In humans, after a brief incubation period of 3 to 5 days, lesions begin as pruritic erythematous macules and then rise to form papules, often with a target appearance. Lesions become nodular or vesicular, and orf lesions often ulcerate after 14 to 21 days. Erythema multiforme and bullous pemphigoid have been associated with parapoxvirus infections and they are rare complications of orf disease. In this case report, we presented a 36-year-old woman with history of contact with sheep, developing a typical orf lesion that is complicated with erythema multiforme and bullous pemphigoid-like eruptions.

Highlights

Parapoxviruses are common pathogens of sheep, goats, and cattle [1] and chamois [2]
Parapoxvirus infection in sheep and goats is usually referred to as sore mouth, scabby mouth, contagious pustular dermatitis/ecthyma, or orf, and the corresponding human infection is referred to as orf
Erythema multiforme and bullous pemphigoid have been associated with parapoxvirus infections and they are very rare complications of orf [1]

Summary

Introduction

Human infection, characterized by localized epithelial lesions, is an occupational hazard for those who handle infected animals. Parapoxvirus infection in sheep and goats is usually referred to as sore mouth, scabby mouth, contagious pustular dermatitis/ecthyma, or orf, and the corresponding human infection is referred to as orf. The relevant parapoxvirus species is referred to as Orf virus; synonyms are contagious pustular dermatitis virus and contagious ecthyma virus. Infection manifests as localized lesions at the site of inoculation by a diseased animal. Milker’s nodules, known as paravaccinia and pseudovaccinia, are cutaneous lesions caused by infection with parapoxvirus of bovine origin. Erythema multiforme and bullous pemphigoid have been associated with parapoxvirus infections and they are very rare complications of orf [1]. We describe a case of orf disease that appeared with erythema multiforme and bullous pemphigoid-like eruptions

Case Report

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