A case of optic neuritis incidentally detected by somatostatin receptor scintigraphy

Abstract

An 18-year-old female patient with increased serum chromogranin-A value (100 U/L; normal value < 90 U/L) underwent somatostatin receptor scintigraphy (SRS) with 111In-pentetreotide searching for the presence of a neuroendocrine tumor. SRS was performed after i.v. administration of 200 MBq of 111In-pentetreotide. Whole-body scans were obtained 4 h and 24 h after the radiopharmaceutical administration and completed by tomographic images (SPECT) of the head, neck, thorax, abdomen and pelvis, performed 24 h after the radiopharmaceutical injection. Whole-body SRS at 4 h was normal. SPECT images performed at 24 h showed an area of linear and moderately increased radiopharmaceutical uptake corresponding to the left orbitary region (Fig. 1A). No other areas of increased radiopharmaceutical uptake were detected in the rest of the body.