A case of non-syndromic multiple odontogenic keratocyst with isolated dentigerous cyst: A diagnostic conundrum

Abstract

Odontogenic keratocyst (OKC) is a common developmental odontogenic cyst affecting the maxillofacial region. They can occur in two different forms, either as solitary (non-syndromic OKCs) or as multiple OKCs (syndromic OKCs). Multiple OKCs are usually seen in association with Gorlin–Goltz syndrome or otherwise called nevoid basal cell carcinoma syndrome. However, approximately 5% of patients with OKC have multiple cysts without concomitant syndromic presentation. This article reports a case of multiple OKCs of orthokeratinised variant in a non-syndromic patient along with an isolated dentigerous cyst associated with impacted teeth in one of the quadrants. Simultaneous occurrence of dentigerous cyst along with multiple OKCs may be coincidental. Impacted teeth must be radiographed and evaluated histopathologically to rule out varied lesions and associated complications with them.