Abstract
Burkholderia pseudomallei is an free-living gram-negative bacterium causing melioidosis and is endemic in Southeast Asia. A 56-year-old diabetic construction worker with a 1-month history of abdominal pain and 1-day history of high-grade fever was found to have a left non-dissecting infrarenal mycotic aortic aneurysm by abdominal computerized tomography scan. Bacteriological examination of his blood yielded Burkholderia pseudomallei. The patient was treated with right axillo-bifemoral bypass with excision of aneurysm and high-dose intravenous ceftazidime for two weeks, followed by oral trimethoprim/sulfamethoxazole and oral doxycycline for a minimum of five months.
Highlights
Burkholderia pseudomallei is considered as a biological threat for its aerosol dissemination and severe impact on human health
Burkholderia pseudomallei associated with mycotic aneurysm is a rare presentation and is found in
The usual etiological agents in mycotic aneurysms are Staphylococcus aureus and non-typhoidal Salmonella species.[2]. This is a case of mycotic aneurysm due to Burkholderia pseudomallei that has rarely been observed
Summary
Burkholderia pseudomallei is considered as a biological threat for its aerosol dissemination and severe impact on human health. 1% - 2% of cases related to high rates of morbidity, mortality, and relapse.[1] The usual etiological agents in mycotic aneurysms are Staphylococcus aureus and non-typhoidal Salmonella species.[2] This is a case of mycotic aneurysm due to Burkholderia pseudomallei that has rarely been observed. In this presentation, clinical findings, laboratory investigations and management of mycotic aneurysms are described. A contrasted abdominal CT scan showed a left infrarenal aortic aneurysm. He was referred to Universiti Kebangsaan Malaysia Medical Centre (UKMMC) for further management. He was advised to take oral antibiotic therapy for a minimum of five months
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