Abstract
A 35 year-old woman developed trigeminal neuropathy in the early course of mixed connective tissue disease (MCTD) . She had Raynaud's phenomenon, swollen finger, myalgia, muscle weakness, arthritis, skin eruption, oral sicca symptom, and unilateral trigeminal neuropathy. Serological study revealed positive antinuclear antibody of speckled pattern and solitary anti RNP antibody. These clinical manifestations and serological studies were compatible with MCTD. Trigeminal neuropathy in association with various connective tissue diseases were discussed. Trigeminal neuropathy was thought to be a rare condition in conective tissue diseases such as sclero derma, polymyositis, systemic lupus erythematosus, and so on. But, this condition had been seen more frequently in the overlapping type of some connective tissue diseases, especially in MCTD.
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