Abstract
We report herein on a case of methotrexate-associated lymphoproliferative disorder (MTX-LPD) presenting with a right parotid swelling and facial nerve palsy. A 69-year-old woman with 4-year rheumatoid arthritis (RA) history with MTX medication and Sjögren’s syndrome presented with a right parotid swelling. Although she was treated on occasions with antibiotics and oral steroids for 4 months, the swelling grew bigger and more painful, then facial nerve palsy appeared. She underwent a biopsy of the right parotid gland, revealing a diffuse large B-cell lymphoma. After MTX withdrawal, the parotid swelling shrank and the facial nerve palsy resolved almost simultaneously within several weeks. She had no evidence of recurrence for 6 months.
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