A case of Marfan syndrome with ischemic stroke due to middle cerebral artery dissection

Abstract

AbstractMarfan syndrome is known to cause aneurysm and dissection of the aorta and cerebral artery. Although there are many reports of dissection of the aorta, there are few of intracranial artery dissection. We report a 32‐year‐old man with Marfan syndrome. He was presented to our hospital with sudden left hemiparesis and dysarthria. The initial diffusion‐weighted image revealed high‐intensity lesions in the right corona radiata. Magnetic resonance angiography revealed the disruption of the blood flow signal in the proximal M1 portion of the right middle cerebral artery. The clinical course of acute occlusion and gradual recanalization was confirmed, and we diagnosed the dissection of the right middle cerebral artery. Anticoagulant therapy was started, and the neurological symptoms disappeared about 1 week after the onset. In Marfan syndrome, dissection of the intracranial cerebral artery is rare, so further investigation is required.