Abstract

A 79-year-old man was seen at the hospital because of left upper abdominal pain on January 4, 1996. Abdominal CT and an ultrasonogram revealed a solid tumor 2.7×2.9cm in size of the spleen which was hypovascular on angiography. No another tumor except for the spleen was revealed on chest and abdominal CT, nor ultrasonography. The bone marrow puncture revealed no abnormal findings. Since the patient refused the operation, outpatient basis follow up was scheduled. Three months later, the tumor grew to 3.5×3.8cm in size, so the patient accepted surgery and an open splenectomy was done. During surgery, no intraabdominal lymphnode swelling was detected, but a sharply demarcated tumor localized in the spleen was noted. The histopathological diagnosis was malignant lymphoma (diffuse large cell type). Three courses of adjuvant chemotherapy with CHOP were conducted. There have been no signs of recurrence, and the patient is under clinical observation on an ambulant basis. This case is valuable because of awaring of the natural history of the tumor. Doubling time of the tumor was caliculated about 210 days.

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