A CASE OF LIVER RESECTION FOR METACHRONOUS AND MULTIPLE LIVER METASTASES OF GASTROINTESTINAL STROMAL TUMOR OF THE STOMACH

Abstract

A 39-year-old man underwent a proximal gastrectomy in October 1997 for a preoperatively diagnosed submucosal tumor located in the upper stomach, and the pathological postoperative diagnosis of the tumor was gastrointestinal stromal tumor (GIST), uncommitted type. In October 1998, abdominal CT study revealed multiple liver tumors, and by abdominal ultrasonography and abdominal MRI study, the liver tumors were diagnosed as multiple metastases of the gastric GIST. In December, right hepatectomy and partial hepatectomy on S1, S3, and S4 segments were performed, and a hepatic arterial infusion port was implanted. Pathologically, liver tumor cells were similar to the primary gastric tumor cells, therefore, the liver tumor was diagnosed as metastases of the gastric GIST, uncommitted type. About 1 year is passed after hepatic resection, and no recurrence is detected. Hepatic resection seems to be effective therapy for liver metastasis of the gastric GIST as well as liver metastasis of the gastric leiomyosarcoma.