Abstract
Case Reports1 November 1953A CASE OF HYPOPLASTIC ANEMIA WITH SECONDARY THROMBOCYTOPENIC PURPURA FOLLOWING THE USE OF CHLORAMPHENICOLHARRY E. THOMPSON, M.D., F.A.C.P., HAROLD J. ROWE, M.D.HARRY E. THOMPSON, M.D., F.A.C.P.Search for more papers by this author, HAROLD J. ROWE, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-39-5-1124 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThis is the report of a case of hypoplastic anemia with secondary thrombocytopenia, following the therapeutic use of chloramphenicol. Although a number of cases have appeared in recent literature,1, 2, 3, 4, 5this one was deemed to be of more than usual interest and is reported for the following reasons: (1) the immediate, but not complete, control of hemorrhage by the use of concentrated platelet infusion, as described by Minor, Burnett et al.6; (2) the temporary palliative effect on the process of ACTH and cortisone; and (3) the ineffectiveness of these and other measures to prevent a fatal termination....Bibliography1. HargravesMilesHeck MMSDFJ: Aplastic anemia associated with administration of chloramphenicol, J. A. M. A. 149: 1293 (Aug. 2) 1952; Proc. Staff Meet., Mayo Clin. 27: 280 (July 16) 1952. CrossrefGoogle Scholar2. RheingoldSpurling JJCL: Chloramphenicol and aplastic anemia, J. A. M. A. 149: 1301 (Aug. 2) 1952. CrossrefGoogle Scholar3. RichRitterhoffHoffman MLRJRJ: A fatal case of aplastic anemia following chloramphenicol (Chloromycetin) therapy, Ann. Int. Med. 33: 1459 (Dec.) 1950. LinkGoogle Scholar4. Loyd EL: Aplastic anemia due to chloramphenicol, Antibiotics and Chemotherapy 2: 1 (Jan.) 1952. Google Scholar5. WilsonHarrisHenstillWitherbeeKahn LEMHHOOJ: Aplastic anemia following prolonged use of chloramphenicol, J. A. M. A. 149: 231 (May 17) 1952. CrossrefMedlineGoogle Scholar6. MinorBurnett AHL: Personal communication. Google Scholar7. ScalettarMazursky HEMD: Secondary thrombocytopenic purpura following D. D. T. exposure, New York State J. Med. 52: 2808 (Nov. 15) 1952. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Tucson, Arizona*Chloromycetin.†Received for publication April 11, 1953. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 November 1953Volume 39, Issue 5Page: 1124-1129KeywordsAdrenocorticotropic hormoneAplastic anemiaChloramphenicolGratitudeHemorrhagePathologistsPlatelets ePublished: 1 December 2008 Issue Published: 1 November 1953 PDF downloadLoading ...
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