Abstract
A 77-year-old man was admitted to the hospital because of anorexia and vomiting. Upper GI series and gastric endoscopy revealed a nodular tumor locating at the antrum and its resulting pyloric stenosis. A biopsied specimen of the tumor showed moderately differentiated adenocarcinoma and the tumor was associated with a high serum alpha-fetoprotein (4232ng/ml). At surgery, a Borrmann I type tumor, measuring 6×4.5×3cm was located at the pre-pylorus, invading the doudenal bulb. No distant metastasis was noted and a subtotal distal gastrectomy was performed. Histological examination revealed trabecular pattern of the tumor cells, and immunohistochemical AFP staining was positive. With these findings, it is considered that the case is of typical hepatoid adenocarcinoma of the stomach.
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