Abstract
Introduction: Scleroderma is an autoimmune connective tissue disease characterized by pervasive systemic multiple organ fibrosis. Definitive diagnosis can be difficult as this disease has a highly variable disease spectrum and course. Further complicating matters, there exist several less commonly known imitators, termed pseudosclerodermas, which force a more open differential than might be presumed initially. Case Report: We present the case of a 46-year-old female diagnosed with pseudoscleroderma. Conclusion: This case emphasizes the importance of skin biopsy while not on steroids and also the need to maintain a broad differential even in the setting of biopsy results. (This page in not part of the published article.) International Journal of Case Reports and Images, Vol. 6 No. 9, September 2015. ISSN – [0976-3198] Int J Case Rep Images 2015;6(9):546–551. www.ijcasereportsandimages.com Sizemore et al. 546 CASE REPORT OPEN ACCESS A case of hardening of the skin and scleroderma like changes on biopsy: Is it scleroderma or not? A review of pseudoscleroderma and differential diagnosis Travis C. Sizemore, Gulzar Merchant, Katharine Whitfield
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