A case of familial amyloidotic polyneuropathy with a rare Phe33Leu mutation in the TTR gene

Abstract

Department of Physiology, National Taiwan University College of Medicine, Taipei, TaiwanReceived 16 July 2012; accepted 23 July 2012Familial amyloidotic polyneuropathy (FAP) is a hereditarypolyneuropathy caused by transthyretin (TTR) mutation,and characterized by length-dependent sensorimotor pol-yneuropathy, autonomic dysfunction, and visceral organinvolvement.