A case of double primary cancers of uterine endometrium and bladder with unusual histology

Abstract

A case of a moderate differentiated endometrial carcinoma of the uterus with a synchronous poorly differentiated bladder cancer is reported. A review of the literature revealed that simultaneous presentation of primary endometrial and bladder neoplasm is rare and usually related to low-stage bladder lesions in contrast to our case with undifferentiated and the deep myometrial invasion of bladder lesion. A 79-year-old woman with endometrial cancer stage IB was performed of total abdominal hysterectomy with bilateral salpingo-oophorectomy, pelvic and para-aortic lymph nodes dissection and adjuvant concurrent cisplatin-radiation therapy. After treatment, she complained intermittent gross hematuria. She was performed the bladder mucosal biopsy and fi nally diagnoses with poorly differentiated carcinoma of bladder. She received transurethral resection of bladder tumor alone without total cystectomy or any other adjuvant treatment due to her refusal. Her condition is tolerable except intermittent hematuria and anemia.