Abstract
The Galle Medical Journal is published by the Galle Medical Association. The journal is published quarterly in March, June, September and December each year. The submissions are accepted throughout the year. The aims of the Journal are to foster co-operation among the medical fraternity and to be a forum to make literary contributions, share experiences encountered in medical practice, update their knowledge and have debates on topics related to all aspects of medicine.
Highlights
Castleman disease, known as Giant lymph node hyperplasia or Angiofollicular lymph node hyperplasia, is a disease of lymph nodes and related tissues
Castleman disease usually presents with fever, weight loss, fatigue, night sweats, infections and anaemia
Pulmonary hypertension has been rarely reported in association with multicentric Castleman disease
Summary
Known as Giant lymph node hyperplasia or Angiofollicular lymph node hyperplasia, is a disease of lymph nodes and related tissues. On examination he was emaciated, pale and had large, discrete, firm and non-tender lymphadenopathy in the cervical, axillary and inguinal regions. He had cardiomegaly, a grade 4 pansystolic murmur best heard in the lower sternum and radiating to the axilla and a loud pulmonary second heart sound. Respiratory system was normal except for few bilateral fine basal crepitations. Abdominal examination showed a 5 cm hepatomegaly and splenomegaly. His haemoglobin was 9.9 g/dL while white cell and platelet counts were normal.
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