Abstract
A case of Buschke-Lowenstein tumor with hypogastric extension
Highlights
Giant condyloma acuminata, known by the eponym Buschke-Lowenstein tumor (BLT), is a human papillomavirus (HPV) –associated verrucous carcinoma of the anogenital region [1]
Buschke-Löwenstein tumor (BLT) is a rare sexuallytransmitted disease (STD) [2], with an incidence of approximately 0.1% in the general population [3], whose main risk factor is the infection with the Human Papilloma Virus (HPV) [4]
BLT is characterized by an invasive growth, a high rate of recurrence to the treatment and likely potential of malignant transformation [2]
Summary
Known by the eponym Buschke-Lowenstein tumor (BLT), is a human papillomavirus (HPV) –associated verrucous carcinoma of the anogenital region [1]. BLT is characterized by an invasive growth, a high rate of recurrence to the treatment and likely potential of malignant transformation (squamous cell adenocarcinoma) [2] Since this disease is rare and no controlled studies exist, radical excision of this anogenital lesion is generally recommended as the first line therapy and close vigilance and follow-up are essential [5]. Intraarterial chemotherapy with agents such as methotrexate has been successfully utilized in verrucous carcinoma of different parts of the body, including the anogenital region This modality may be used as neoadjuvant therapy before surgical intervention and in certain cases may obviate the need for surgery. The diagnosis of Buschke-Löwenstein tumor was retained and the patient was referred to the urological surgery for extensive excision
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
