Abstract
A case of bilateral forearm amputation resulting from purpura fulminans following subtotal colectomy for perforated ulcerative colitis
Highlights
Purpura Fulminans (PF) is a complication commonly associated with scarlet fever and meningococcal infection in infants but is reported in adult patients
This case presents an opportunity to discuss the importance of supportive care and hematological treatments to reduce the mortality and control the devastating complications of microvascular coagulation and limb ischemia associated with PF
Purpura fulminans (PF) is a rare syndrome characterized by microvasculature coagulation and thrombosis with hemorrhagic necrosis that can lead to purpuric lesions, skin necrosis and gangrene and autoamputation of distal extremities [1]
Summary
Optimization of microcirculation, steroid treatment, immunomodulation, protein C zymogen, plasma exchange or replacement can potentially mitigate the injury and should be considered to improve outcome
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