A case of atypical cellular chorangioma

Abstract

s / Placenta 36 (2015) A1eA14 A4 CMV-DNA was detected in the blood and urine of the newborn. The placenta immunostaining also showed that anti-CMV antibody was positive. Case 2: A 32-year-old woman was referred to our hospital at 32 weeks’ gestation, because the ultrasound findings of her fetus showed mild lateralventriclemegaly. Any other obvious abnormal findings were not observed. She delivered a 2450g (-1.8SD) newborn without any complications at 39 weeks’ gestation, the Apgar scores were 8/9 points. The ultrasound examination of the newborn detected expanded bilateral polyependymal cysts and dilatation of bilateral ventricles, and the fetal MRI presented similar findings. CMV-DNA was detected in the blood and urine of the newborn. The placenta immunostaining also showed that anti-CMV antibody was positive. Conclusions: We considered that the pathologic examination of placenta after birth was also useful for diagnosis in congenital CMV infection. JPA2015-09. A CASE OF ATYPICAL CELLULAR CHORANGIOMA Akira Kohata , Atsushi Kasamatsu , Hidetaka Okada , Yoshiko Uemura , Sachiko Minamiguchi . Kansai medical university hospital, Japan; Kyouto medical university hospital, Japan Atypical Cellular Chorangioma is rare case. This case is with the blood transfusion syndrome between mother and fetus. Mother is 29years old and pregnancy 29weeks and 5days. When the patient came our hospital, Fetus was no problem. Pregnancy 30weeks and 1day, we found fetus hydrops and placental edema. Because uterine contraction increase in same day and fetus was breech presentation, we did emergency caesarean section. Neonatal was 1414g and Apgar score was 6/7 and newborn’s Hb was 4.0/dl. Mother’s blood examination shows 4.7% of HbF, so we diagnosis the blood transfusion syndrome between mother and fetus. Placental weight is 700g with edema .There is no chorioamnionitis, so we think the edema came from culatory disturbance. We found 5mm nodewhich tissue proliferation increases and Ki-67 was high grade positive and CD31 was positive but no invasion around tissue. So pathological diagnosis was atypical cellular chorangioma. Atypical cellular chorangioma is benign but some report say complication of angioma in baby or mother. We did detailed examination and found that they didn’t have angioma either. It’ s not clear there is relation between atypical cellular chorangioma and blood transfusion syndrome between mother and fetus, but some report says relation of chorangioma and blood transfusion syndrome between mother and fetus. We need to collect more case of atypical cellular chorangioma and study relation between atypical cellular chorangioma and blood transfusion syndrome between mother and fetus. JPA2015-11. AGE AND HMGB1 INDUCES INFLAMMATORY RESPONSE IN HUMAN TROPHOBLAST CELL LINE Kotomi Seno , Koumei Shirasuna , Narumi Shimamura , Shogo Shiratsuki , Akihide Ohkuchi , Hisataka Iwata , Takehito Kuwayama . 1 Tokyo University of Agriculture, Japan; 2 Jichi Medical